Found 12 matching trials
A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State PHASE1 The primary purpose of this study is to evaluate the effect of the up-titra...
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SGS Clinical Pharmacology Unit (located in ZNA Stuivenberg)
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Study to Investigate the Absolute Bioavailability of a Single Oral Dose of Ponesimod in Healthy Male Subjects PHASE1 This study consists of a single-dose pilot phase and a randomized, two-way ...
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Simbec Research Limited
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Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis PHASE3 A multicenter, randomized, double-blind, placebo-controlled study to evalua...
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Vanda Investigational Site
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Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®) PHASE3 This clinical study compares the efficacy, safety, and tolerability of ther...
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UAB Dpt of Neurology
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Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of Ponesimod in Subjects With Symptomatic Chronic GVHD PHASE2 Chronic graft versus host diseasre (GVHD) is a serious reaction that might ...
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Multiple Locations
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Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial NA FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) tar...
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Active Not Recruiting
Location
University of Alabama at Birmingham
Treatments Being Tested
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsq Glatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod Learn More & Join Trial
ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis PHASE2 This study will assess the efficacy, safety and tolerability of two doses o...
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Clinical Investigative Site 1006
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Mass Balance, Pharmacokinetics, and Metabolism of 14C-labeled ACT-128800 Administered to Healthy Male Subjects PHASE1 The study was conducted to investigate the metabolism and mass balance of A...
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Swiss Pharma Contract
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Study of the Electrocardiographic Effects of Ponesimod in Healthy Male and Female Subjects PHASE1 The aim of this study is to demonstrate that therapeutic and supratherapeut...
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Covance Clinical Research Unit (CRU)
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Long-term Extension to Study AC-058B301 to Investigate Safety, Tolerability and Disease Control of Ponesimod 20 mg in Patients With Relapsing Multiple Sclerosis PHASE3 The study AC-058B301 (OPTIMUM; NCT02425644) has been designed to investigat...
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The Research Center of Southern California, LLC
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